Han A. A. van Heugten, Yvonne E. G. Eskildsen-Helmond,'s Biochemistry of Signal Transduction in Myocardium PDF

By Han A. A. van Heugten, Yvonne E. G. Eskildsen-Helmond, Henriette W. de Jonge (auth.), Jos M. J. Lamers, Pieter D. Verdouw (eds.)

ISBN-10: 1461285445

ISBN-13: 9781461285441

ISBN-10: 1461312752

ISBN-13: 9781461312758

Show description

Read or Download Biochemistry of Signal Transduction in Myocardium PDF

Best biochemistry books

Human Brain Proteome by Lisa A. Neuhold (Eds.) PDF

Proteomics is a scientific process for learning the id and serve as of all proteins expressed in a mobilephone, tissue or organ. New drug pursuits for illnesses are frequently pointed out by means of evaluating the proteome of the sickness kingdom to the traditional country. consequently, proteomics has develop into more and more very important within the pharmaceutical and biotechnology industries in addition to teachers.

Fundamentals of Biochemistry: Life at the Molecular Level - download pdf or read online

Content material: advent -- creation to the chemistry of existence -- Water -- Biomolecules -- Nucleotides, nucleic acids, and genetic details -- Amino acids -- Proteins: basic constitution -- Proteins: three-d constitution -- Protein functionality: myoglobin and hemoglobin, muscle contraction, and antibodies -- Carbohydrates -- Lipids and organic membranes -- Membrane delivery -- Enzymes -- Enzymatic catalysis -- Enzyme kinetics, inhibition, and keep watch over -- Biochemical signaling -- Metabolism -- advent to metabolism -- Glucose catabolism -- Glycogen metabolism and gluconeogenesis -- Citric acid cycle -- Electron shipping and oxidative phosphorylation -- Photosynthesis -- Lipid metabolism -- Amino acid metabolism -- Mammalian gasoline metabolism: integration and law -- Gene expression and replication -- Nucleotide metabolism -- Nucleic acid constitution -- DNA replication, fix, and recombination -- Transcription and RNA processing -- Protein synthesis -- rules of gene expression

α-Gal and Anti-Gal: α1,3-Galactosyltransferase, α-Gal - download pdf or read online

This is often an interdisciplinary e-book which for the 1st time assembles the extensive spectrum of knowledge at the easy and scientific points of the usual anti-Gal antibody, the alpha-gal epitope and the enzyme generating it, alpha-1,3-galactosyltransferase. Anti-Gal is the main plentiful antibody in people, apes and outdated international monkeys (monkeys of Asia and Africa).

Extra info for Biochemistry of Signal Transduction in Myocardium

Example text

Although several cardiomyopathies are associated with abnormal GPCR function, mutations are unlikely in these disorders. g. posttranslational modifications; effector regulation by ~'Y subunits; GTPase activating protein (GAP) activity of effectors; G protein expression levels etc. When comparing the regulation of G protein functional activity in cAMP and in inositol phosphate generating pathways, an extrapolation can be made to data on the status of these pathways in some cardiovascular diseases.

Cardiovasc Res 28: 1451-1460, 1994 5. Strader CD, Fong TM, Tota MR, Underwood D, Dixon RAF: Structure and function of G protein-coupled receptors. Annu Rev Biochem 63: 101-132,1994 6. Linder ME, Ewald DA, Miller RJ, Gilman AG: Purification and charaterization of GOa and three types of G;a after expression in Escherichia coli. J Bioi Chern 265: 8243-8251, 1990 7. Neer EJ: Heterotrimeric G proteins: Organizers of transmembrane signals. Cell 80: 249-257, 1995 8. Hansen CA, Schroering AG, Robishaw JD: Subunit expression of signal transducing G proteins in cardiac tissue: Implications for phospholipase C-beta regulation.

However, since it is an irreversible process, it has no regulatory function. Palmitoylation, on the contrary, is reversible. g. ,I a q) are palmitoylated at an amino-terminal cysteine residue. Depalmitoylation of a, has been observed after ~adrenoceptor stimulation. The depalmitoylated form was inactive and translocated to the cytosol [27, 28]. The precise significance of this mechanism is not clear yet. Phospholipase C-o In one recent study, the GPCR activation of phospholipase C-O has been shown, but the mechanism is still under speculation [25].

Download PDF sample

Biochemistry of Signal Transduction in Myocardium by Han A. A. van Heugten, Yvonne E. G. Eskildsen-Helmond, Henriette W. de Jonge (auth.), Jos M. J. Lamers, Pieter D. Verdouw (eds.)


by Steven
4.3

Rated 4.59 of 5 – based on 27 votes