By Brian J Arey
Biased Signaling in body structure, Pharmacology and Therapeutics is a distinct and crucial reference for the clinical group touching on how conformational-dependent activation is a typical phenomenon throughout many periods of receptors or signaling molecules. Written for either new and verified scientists in pharmacology, mobile biology, biochemistry, and sign transduction, in addition to physicians, this ebook sincerely explains biased signaling as an advanced mechanism for physiological platforms to decipher complicated signs from a restricted variety of signaling mechanisms. each one bankruptcy is devoted to another type of receptor and discusses the clinical foundation for biased signaling within the context of ways this information impacts pharmacology and will be used to enhance medicinal drugs and deal with ailment.
- Offers a distinct and helpful source on biased receptor signaling that offers a world view for higher figuring out pharmacology throughout many receptor families
- Integrates biased receptor signaling, body structure, and pharmacology to put this rising technology in the context of treating ailment
- Includes very important chapters on either the pharmaceutical and healing implications of biased signaling
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Extra info for Biased signaling in physiology, pharmacology and therapeutics
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14 depicts some of the key aspects of understanding the pharmacological effects of ligands. Synthetic ligands that mimic the effects of the naturally occurring ligand, for example on signal transduction, are defined as agonists. Compounds that block, or antagonize, the effects of a naturally occurring ligand are said to be antagonists. The nature of a compound as an agonist or antagonist is determined by studying the effects of the compound on the biological end point in a concentrationÀresponse experiment.
Biased signaling in physiology, pharmacology and therapeutics by Brian J Arey